(R)-1-苯基-2-丙醇合成路线 （共 57 条）
反应条件
nickel in tetrahydrofuran 2 h; Ambient temperature;
参考文献
Tetrahedron: Asymmetry, , vol. 2, # 4 p. 257 - 276
反应条件
4 A molecular sieve; chiral diamine; triethylamine in dichloromethane T=-78°C; 3 h; Yield givenYields of byproduct given;
参考文献
Chemistry Letters, , # 3 p. 265 - 266
反应条件
1: 56 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.5 h / Ambient temperature 2: Raney-nickel / tetrahydrofuran / 2 h / Ambient temperature View Scheme
参考文献
Tetrahedron: Asymmetry, , vol. 2, # 4 p. 257 - 276
反应条件
1: borane / Corey catalyst / 0.5 h / Ambient temperature 2: 80 percent / EtOH / Raney nickel / 50 °C / or nBu3SnH, AIBN, toluene, reflux View Scheme
参考文献
Tetrahedron Letters, , vol. 31, # 51 p. 7415 - 7418
反应条件
hydrogen cation in water Yield given;
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1330 - 1354
反应条件
sodium hydroxide in methanol; water
参考文献
Tetrahedron Asymmetry, , vol. 17, # 15 p. 2220 - 2234
反应条件
1: triethylamine / 3 h / 75 - 80 °C 2: aq. LiOH / methanol / 3 h / 20 °C View Scheme
参考文献
Journal of Chemical Research, , # 10 p. 681 - 683
反应条件
1: ruthenium / water / 24 h / 60 °C / |Sealed tube; |Inert atmosphere 2: C38H46O3P2*C7H8*Rh(1+)*BF4(1-); hydrogen / dichloromethane / 24 h / 40 °C / 3000.3 Torr / |Glovebox; |Inert atmosphere 3: potassium carbonate; methanol / 16 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 48 p. 16209 - 16212
反应条件
1: C38H46O3P2*C7H8*Rh(1+)*BF4(1-); hydrogen / dichloromethane / 24 h / 40 °C / 3000.3 Torr / |Glovebox; |Inert atmosphere 2: potassium carbonate; methanol / 16 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Chemistry - A European Journal, , vol. 19, # 48 p. 16209 - 16212
反应条件
water T=30°C; 168 h; asymmetric hydrolysis and resolution by Pseudomonas cepacia; Product distribution;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 58, # 7 p. 1330 - 1331
