2-苯基-1,3-丙二醇合成路线 （共 45 条）
反应条件
diisobutylaluminium hydride in tetrahydrofuran 2 h; Ambient temperatureother reducing agents, var. time; MechanismProduct distribution;
参考文献
Choi, Yong M.; Emblidge, Robert W.
Journal of Organic Chemistry, 1989 , vol. 54, # 5 p. 1198 - 1200
反应条件
hydrogenchloride; sodium borohydride; tetrabutyl-ammonium chloride; sodium carbonate in tert-butyl methyl ether; water
参考文献
Ganes Chemicals Inc.
Patent: US5250744 A1, 1993 ;
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 20°C; 12 h; Heating / reflux;
参考文献
WO2007/81570 A2, ;
Page/Page column 27 ;
反应条件
water; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) in acetonitrile T=20°C; 5 h;
参考文献
Liu, Junjie; Wong, Chi-Huey
Tetrahedron Letters, 2002 , vol. 43, # 22 p. 4037 - 4039
反应条件
sodium tetrahydroborate; bromine in ethylene glycol dimethyl ether T=-10 - 20°C; 0.5 h;
参考文献
Tudge, Matthew; Mashima, Hiroko; Savarin, Cecile; Humphrey, Guy; Davies, Ian
Tetrahedron Letters, 2008 , vol. 49, # 6 p. 1041 - 1044
反应条件
sodium tetrahydroborate; sodium dihydrogenphosphate
参考文献
TARO PHARMACEUTICAL INDUSTRIES LTD.; GUTMAN, Daniella; BAIDOSSI, Wael; BERCOVICI, Sorin; CHERNIAK, Simon
Patent: WO2012/32508 A1, 2012 ;
Location in patent: Page/Page column 7 ;
反应条件
borane in tetrahydrofuran T=-30°C; 144 h;
参考文献
Choi, Yong M.; Emblidge, Robert W.; Kucharczyk, Norbert; Sofia, R. Duane
Journal of Organic Chemistry, 1989 , vol. 54, # 5 p. 1194 - 1198
反应条件
palladium in methanol; hydrogen; toluene
反应条件
Na(PEG-400)2BH2 in tetrahydrofuran T=80°C; 4 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 4 p. 671 - 674
反应条件
Bacillus cereus 809A in phosphate buffer T=30°C; pH=7.0; Title compound not separated from byproducts.;
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 71, # 8 p. 1858 - 1864
