(R)-(+)-1-苯基-1-丙醇合成路线 (共 130 条)
反应条件
lithium aluminium tetrahydride in diethyl ether 6 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 7, # 11 p. 3285 - 3294
反应条件
sodium hydroxide; (-)-isopinocampheylborane; dihydrogen peroxide 1) THF, -25 deg C, 9 h, 2) 50 deg C, 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 46, # 24 p. 5047 - 5048
反应条件
sodium tetrahydroborate; chloro-trimethyl-silane; (S)-(-)-α,α-diphenyl-2-pyrrolidinemethanol in tetrahydrofuran T=25 - 70°C; 1 h;
参考文献
Tetrahedron Letters, , vol. 41, # 52 p. 10281 - 10283
反应条件
air; cells of Geotrichum candidum IFO 5767 in water T=30°C; 24 h;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 22 p. 3147 - 3153
反应条件
hydrogenchloride; (-)-DAIB in toluene T=0°C;
参考文献
Journal of the American Chemical Society, , vol. 111, # 11 p. 4028 - 4036
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate in tetrahydrofuran; methanol 10 h; Ambient temperature; Yield given;
参考文献
Tetrahedron: Asymmetry, , vol. 4, # 12 p. 2419 - 2422
反应条件
(R)-5-CF3-2-Ph-2,3-dihydroimidazo[1,2-a]pyridine; N-ethyl-N,N-diisopropylamine in chloroform 8 h; cooling; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 126, # 39 p. 12226 - 12227
反应条件
sodium hydroxide; (S)-1-(2-diphenylphosphino-1-naphthyl)isoquinoline rhodium; dihydrogen peroxide; benzo[1,3,2]dioxaborole 1.) THF, RT, 2 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron: Asymmetry, , vol. 6, # 10 p. 2593 - 2596
反应条件
1: With trimethylsilyl trifluoromethanesulfonate; benzo[1,3,2]dioxaborole; [Rh(acac)(COD)]2; (R)-1-(2-phenylquinazolin-4-yl)-2-(Ph2P)-naphthalene in tetrahydrofuran T=25°C; Addition; Hydroboration; 2 h; 2: With sodium hydroxide; dihydrogen peroxide in tetrahydrofuran T=20°C; Oxidation; Hydrolysis; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Chemical Communications, , # 14 p. 1333 - 1334
反应条件
Sphingomonas paucimobilis NCIMB 8195 in water; N,N-dimethyl-formamide 120 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 19 p. 6495 - 6497