hydrogenchloride in methanol; water T=0 - 5°C; 2.5 h;

1.1: copper(I) bromide; zinc dibromide / tetrahydrofuran / 21.5 h / 60 °C 2.1: pyridine / dichloromethane / 2.83 h / -30 - 0 °C 3.1: sodium azide / acetonitrile / Inert atmosphere; Reflux 4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / -15 - 5 °C / Inert atmosphere 4.2: 1 h / -5 - 5 °C / Inert atmosphere 4.3: 1.5 h / Inert atmosphere 5.1: hydrogenchloride / water; methanol / 2.5 h / 0 - 5 °C View Scheme

1.1: pyridine / dichloromethane / 2.83 h / -30 - 0 °C 2.1: sodium azide / acetonitrile / Inert atmosphere; Reflux 3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / -15 - 5 °C / Inert atmosphere 3.2: 1 h / -5 - 5 °C / Inert atmosphere 3.3: 1.5 h / Inert atmosphere 4.1: hydrogenchloride / water; methanol / 2.5 h / 0 - 5 °C View Scheme

1.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / -15 - 5 °C / Inert atmosphere 1.2: 1 h / -5 - 5 °C / Inert atmosphere 1.3: 1.5 h / Inert atmosphere 2.1: hydrogenchloride / water; methanol / 2.5 h / 0 - 5 °C View Scheme