反应条件
1: 1.) sodium borohydride, 2.) 6 M aq. HCl / methanol / 1 h / 0 °C 2: Et3N / CH2Cl2 / 1 h / Ambient temperature 3: DBU / tetrahydrofuran / 24 h / Ambient temperature 4: 96 percent / aq. KOH / methanol / 2 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 17 p. 3398 - 3406