potassium carbonate in N,N-dimethyl-formamide T=20°C; 0.5 h;

1: 1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione With pyridine; palladium diacetate; copper (II) acetate monohydrate; copper(l) chloride in N,N-dimethyl acetamide T=20°C; Heck reaction; 0.0833333 h; Inert atmosphere; 2: 1,2-dimethoxy-4-ethenyl-benzene in N,N-dimethyl acetamide T=120°C; Heck reaction; 20 h; Inert atmosphere;

1: 65 percent / pyridine / CH2Cl2 / 16 h / 20 °C 2: 92 percent / 1,1,1,3,3,3-hyxamethyldisilazane; (NH4)2SO4 / 4 h / 170 - 180 °C 3: 95 percent / potassium carbonate / dimethylformamide / 0.5 h / 20 °C View Scheme

1: 80 percent / NH3; sodium dithionite / H2O / 60 °C 2: 65 percent / pyridine / CH2Cl2 / 16 h / 20 °C 3: 92 percent / 1,1,1,3,3,3-hyxamethyldisilazane; (NH4)2SO4 / 4 h / 170 - 180 °C 4: 95 percent / potassium carbonate / dimethylformamide / 0.5 h / 20 °C View Scheme

1: 74 percent / acetic acid; NaNO2 / H2O / 0.25 h / 50 - 60 °C 2: 80 percent / NH3; sodium dithionite / H2O / 60 °C 3: 65 percent / pyridine / CH2Cl2 / 16 h / 20 °C 4: 92 percent / 1,1,1,3,3,3-hyxamethyldisilazane; (NH4)2SO4 / 4 h / 170 - 180 °C 5: 95 percent / potassium carbonate / dimethylformamide / 0.5 h / 20 °C View Scheme

1: 92 percent / 1,1,1,3,3,3-hyxamethyldisilazane; (NH4)2SO4 / 4 h / 170 - 180 °C 2: 95 percent / potassium carbonate / dimethylformamide / 0.5 h / 20 °C View Scheme

1.1: EDAC / dioxane; H2O 1.2: 35 percent / aq. NaOH / Heating 2.1: K2CO3 / dimethylformamide View Scheme

1.1: acetic acid / 2 h / 80 °C 2.1: sodium nitrite / acetic acid / 0.25 h / 50 - 60 °C 3.1: ammonium hydroxide; sodium dithionite / water / 0.5 h 4.1: pyridine / dichloromethane / 24 h / 20 °C 5.1: acetonitrile / |Microwave irradiation 5.2: 5 h / 160 °C / |Microwave irradiation 6.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C View Scheme

1.1: pyridine / dichloromethane / 24 h / 20 °C 2.1: acetonitrile / |Microwave irradiation 2.2: 5 h / 160 °C / |Microwave irradiation 3.1: potassium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C View Scheme