3-氨基-2-甲基-1-丙醇合成路线 (共 5 条)
反应条件
1: With boron trifluoride diethyl etherate in tetrahydrofuran 3.5 h; RefluxInert atmosphere; 2: With dimethylsulfide borane complex in methanethiol 6 h; RefluxInert atmosphere; 3: With sodium hydroxide in tetrahydrofuran; water 15 h; RefluxInert atmosphere;
参考文献
Hansen, Camilla P.; Jensen, Anders A.; Christensen, Jeppe K.; Balle, Thomas; Liljefors, Tommy; Frolund, Bente
Journal of Medicinal Chemistry, 2008 , vol. 51, # 23 p. 7380 - 7395
参考文献
Dicko, A.; Montury, M.; Baboulene, M.
Tetrahedron Letters, 1987 , vol. 28, # 48 p. 6041 - 6044
反应条件
hydrogenchloride; thionyl chloride in potassium hydroxide; diethyl ether; dichloromethane
参考文献
Pfizer Inc.
Patent: US6133286 A1, 2000 ;
US 6133286 A
参考文献
Brown, Pamela; Southgate, Robert
Tetrahedron Letters, 1986 , vol. 27, # 2 p. 247 - 250
参考文献
Brown, Pamela; Southgate, Robert
Tetrahedron Letters, 1986 , vol. 27, # 2 p. 247 - 250