2,3-二氯-4-氟苯甲酸合成路线 （共 3 条）
反应条件
N,N,N',N,-tetramethylethylenediamine; 1,2,2-trichloro-1,1,2-trichloro-ethane; sec.-butyllithium in tetrahydrofuran 1.) -90 deg C, 30 min, 2.) -78 deg C;
参考文献
Bennetau, Bernard; Mortier, Jacques; Moyroud, Joel; Guesnet, Jean-Luc
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 10 p. 1265 - 1272
反应条件
potassium dichromate; sulfuric acid in acetic acid T=100°C; 2 h;
参考文献
US2008/9541 A1, ;
Page/Page column 27 ;
反应条件
1: triethylamine; diphenylphosphorylazide / Heating 2: HCl / diethyl ether / 20 °C View Scheme
参考文献
Nelson, Derek W.; Gregg, Robert J.; Kort, Michael E.; Perez-Medrano, Arturo; Voight, Eric A.; Wang, Ying; Grayson, George; Namovic, Marian T.; Donnelly-Roberts, Diana L.; Niforatos, Wende; Honore, Prisca; Jarvis, Michael F.; Faltynek, Connie R.; Carroll, William A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 12 p. 3659 - 3666
