3-(2-溴乙酰基)噻吩-2-磺酰胺合成路线 （共 2 条）
反应条件
1: With toluene-4-sulfonic acid in acetonitrile T=20°C; 0.5 h; 2: With N-bromosuccinmide in acetonitrile 2 h; Heating / reflux;
参考文献
Sathe, Dhananjay Govind; Tarur, Radhakrishnan Venkatasubramanian; Bhise, Nandu Baban; Shinde, Ajit Bhaskar; Pardeshi, Santosh
Patent: US2010/9977 A1, 2010 ;
Location in patent: Page/Page column 11 ;
反应条件
1: With sodium tetrahydroborate in tetrahydrofuran
T=20°C; 16 h;
2: With sodium hydroxide in tetrahydrofuran
T=20°C; 24 h;
3: With hydrogenchloride in tetrahydrofuran; water
pH=7;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2010/317655 A1, 2010 ;
Location in patent: Page/Page column 15 ;
