2,4,6-三甲基苯硫酚合成路线 （共 29 条）
参考文献
Grillot; Schaffrath
Journal of Organic Chemistry, 1959 , vol. 24, p. 1035,1036
参考文献
Grillot et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 3969
参考文献
Grillot et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 3969
反应条件
1: potassium carbonate / dichloromethane / 20 h / 20 °C / Inert atmosphere
2: dihydrogen peroxide / 2,2,2-trifluoroethanol; water / 0 - 20 °C
3: (1S,2S,4S,5R)-1-(anthracen-9-ylmethyl)-2-((R)-hydroxy(quinolin-4-yl)methyl)-5-vinyl-1-azoniabicyclo[2.2.2]octane chloride; sodium hydroxide / dichloromethane; water; toluene / 0 °C / Inert atmosphere
View Scheme
参考文献
Tudorache, Madalina; Nica, Simona; Bartha, Emerich; Lupan, Iulia; Parvulescu, Vasile I.
Applied Catalysis A: General, 2012 , vol. 441-442, p. 42 - 46
反应条件
1: (i) Cu2O, EtOH, (ii) /BRN= 2045666/
2: aq. H2O2 / acetic anhydride; acetic acid
View Scheme
参考文献
Truce,W.E.; Guy,M.M.
Journal of Organic Chemistry, 1961 , vol. 26, p. 4331 - 4336
反应条件
caesium carbonate in acetonitrile
16 h; Inert atmosphereReflux;
参考文献
Wiester, Michael J.; Braunschweig, Adam B.; Yoo, Hyojong; Mirkin, Chad A.
Inorganic Chemistry, 2010 , vol. 49, # 15 p. 7188 - 7196
参考文献
Jutzi,P. et al.
Chemische Berichte, 1978 , vol. 111, p. 606 - 614
反应条件
d-(+)-α-methylbenzylamine; (-)-Brucine; quinine powder
T=0 - 40°C; kinetic resolution of title compound up to 81.8percent e.e. in different solvents and conditions; Product distribution;
参考文献
Dell'Erba, Carlo; Novi, Marino; Garbarino, Giacomo; Corallo, Poluzzi Giancarla
Tetrahedron Letters, 1983 , vol. 24, # 11 p. 1191 - 1192
反应条件
(i) Cu2O, EtOH, (ii) /BRN= 2045666/; Multistep reaction;
参考文献
Truce,W.E.; Guy,M.M.
Journal of Organic Chemistry, 1961 , vol. 26, p. 4331 - 4336
