3-正-丁基-2,4-戊烷二酮合成路线 （共 32 条）
反应条件
acetic acid in ethanol 1) reflux, 2) r.t.;
参考文献
Singh, S. P.; Vaid, R. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 288 - 291
反应条件
methanol; sodium chloride electrolysis;
参考文献
Fujimoto, Kazuo; Maekawa, Hirofumi; Matsubara, Yoshiharu; Nishiguchi, Ikuzo
Chemistry Letters, 1996 , # 2 p. 143 - 144
反应条件
sulfuric acid; dihydrogen peroxide in water T=20°C;
参考文献
Terentev, Alexander O.; Borisov, Dmitry A.; Yaremenko, Ivan A.; Ogibin, Yuri N.; Nikishin, Gennady I.
Synthesis, 2010 , # 7 art. no. P14909SS, p. 1145 - 1149
反应条件
acetic acid; zinc 1 h; Heating;
参考文献
Berezin, M. V.; Semeikin, A. S.; V'yugin, A. I.; Krestov, G. A.
Russian Chemical Bulletin, 1993 , vol. 42, # 3 p. 449 - 453
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 3 p. 495 - 499
反应条件
in acetic acid Cyclization; 2 h; Heating;
参考文献
Lash, Timothy D.
Tetrahedron, 1998 , vol. 54, # 3-4 p. 359 - 374
反应条件
sodium acetate; zinc 1.) acetic acid, 80 deg C, 40 min; 2.) acetic acid, 20 min, 95-105 deg C; Yield given. Multistep reaction;
参考文献
Lecas-Nawrocka, Alexandra; Levisalles, Jacques; Mariacher, Claire; Renko, Zafiarisoa; Rose, Eric
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2054 - 2058
参考文献
Akopova; Zdanovich; Akopov; Aleksandrov; Pashkova
Journal of Structural Chemistry, 2001 , vol. 42, # 1 p. 43 - 50
反应条件
1: Zn; AcOH 2: KOH / ethane-1,2-diol View Scheme
参考文献
Klyueva; Lebedev; Nikitin; Semeikin
Russian Journal of General Chemistry, 2006 , vol. 76, # 11 p. 1848 - 1850
反应条件
1: 79 percent / acetic acid / 2 h / Heating 2: 78 percent / acetic anhydride / acetic acid / 3 h / 20 °C 3: 88 percent / conc. HCl / methanol / 3 h / Heating 4: sodium hydroxide / ethane-1,2-diol / 1 h / 180 °C View Scheme
参考文献
Mamardashvili, N. Zh.; Semeikin, A. S.; Golubchikov, O. A.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 6.2 p. 1007 - 1015
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 6 p. 1213 - 1223
反应条件
1: acetoacetic acid benzyl ester With sodium nitrite in water; acetic acid
T=20°C;
2: 3-(n-butyl)-2,4-pentanedione With sodium acetate; zinc in water; acetic acid
T=80 - 90°C; Further stages.;
参考文献
Uno, Hidemitsu; Nakamoto, Ken-Ichi; Kuroki, Kenji; Fujimoto, Akiko; Ono, Noboru
Chemistry - A European Journal, 2007 , vol. 13, # 20 p. 5773 - 5784
