(3R,4S,5R)-3,4-二羟基-5-(羟基甲基)二氢-2(3H)-呋喃酮合成路线 (共 17 条)
参考文献
Wolfrom; Anno
Journal of the American Chemical Society, 1952 , vol. 74, p. 5583
参考文献
Fischer,E.; Bromberg
Chemische Berichte, 1896 , vol. 29, p. 583
反应条件
1.1: 60 percent / CuSO4 / acetone 2.1: Tf2O; pyridine / CH2Cl2 2.2: 89 percent / NaN3 / dimethylformamide 3.1: 97 percent / 4A MS / tetrahydrofuran / -78 °C 4.1: 91 percent / H2 / Pd / methanol View Scheme
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
反应条件
1.1: 60 percent / CuSO4 / acetone 2.1: Tf2O; pyridine / CH2Cl2 2.2: 89 percent / NaN3 / dimethylformamide View Scheme
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
参考文献
Fleet, George W.J.; Petursson, Sigthor; Campbell, Arthur L.; Mueller, Richard A.; Behling, James R.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 665 - 666
参考文献
G. D. Searle and Co.
Patent: US4910310 A1, 1990 ;
反应条件
methanesulfonic acid
T=20°C; 40 h;
参考文献
Fan, Ao; Jaenicke, Stephan; Chuah, Gaik-Khuan
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 22 p. 7720 - 7726