2-(2,3-二甲氧基苯基)丙烷-2-醇合成路线 （共 6 条）
反应条件
1: in tetrahydrofuran T=20°C; 22 h; Reflux; 2: With water; ammonium chloride in tetrahydrofuran
参考文献
Nishimoto, Yoshihiro; Babu, Srinivasarao Arulananda; Yasuda, Makoto; Baba, Akio
Journal of Organic Chemistry, 2008 , vol. 73, # 23 p. 9465 - 9468
反应条件
1: 1,2-dimethoxy-benzene With n-butyllithium in tetrahydrofuran; hexane T=-78 - 0°C; Inert atmosphere; 2: acetone in tetrahydrofuran; hexane T=-60 - 20°C;
参考文献
Martinez-Solorio, Dionicio; Jennings, Michael P.
Organic Letters, 2009 , vol. 11, # 1 p. 189 - 192
反应条件
1.1: n-BuLi / tetrahydrofuran / 1 h / -78 °C 1.2: 98 percent / tetrahydrofuran / 15 h / 20 °C 2.1: 95 percent / tetrahydrofuran / 18 h / 60 °C View Scheme
参考文献
Chin, Chin-Long; Tran, Duong Duc-Phi; Shia, Kak-Shan; Liu, Hsing-Jang
Synlett, 2005 , # 3 art. no. U30404ST, p. 417 - 420
反应条件
1: concentrated H2SO4; 1,2-dichloro-ethane 2: diethyl ether View Scheme
参考文献
Edwards; Cashaw
Journal of Organic Chemistry, 1955 , vol. 20, p. 847
反应条件
1: Ag2O; aqueous NaOH 2: concentrated H2SO4; 1,2-dichloro-ethane 3: diethyl ether View Scheme
参考文献
Edwards; Cashaw
Journal of Organic Chemistry, 1955 , vol. 20, p. 847
反应条件
1: 97 percent / H2, 85percent aq. phosphoric acid / 5percent Pd/C / ethanol / 6 h / 60 °C / 2280 Torr 2: 96 percent / 48percent aq. HBr, acetic acid / 4 h / Heating View Scheme
参考文献
Majetich; Liu
Synthetic Communications, 1993 , vol. 23, # 16 p. 2331 - 2335
