1-苯甲基-1H-吡咯[2,3-b]吡啶合成路线 （共 7 条）
反应条件
1: 1H-Pyrrolo[2,3-b]pyridine With sodium hydride in N,N-dimethyl acetamide Metallation; 0.5 h; 2: benzyl bromide in N,N-dimethyl acetamide T=20°C; Alkylation;
参考文献
Tatsugi, Jiro; Zhiwei, Tong; Amano, Tomohiro; Izawa, Yasuji
Heterocycles, 2000 , vol. 53, # 5 p. 1145 - 1150
反应条件
1,1'-bis(diphenylphosphino)ferrocene; palladium diacetate; caesium carbonate in toluene T=110°C; 6 h; Inert atmosphere;
参考文献
Hodgkinson, Roy C.; Schulz, Jurgen; Willis, Michael C.
Tetrahedron, 2009 , vol. 65, # 44 p. 8940 - 8949
反应条件
sodium hydride in N,N-dimethyl-formamide T=25°C; reactions with other alkylating agents; effect of var. cond.; Product distributionRate constant;
参考文献
Mahadevan, Indumathy; Rasmussen, Malcolm
Tetrahedron, 1993 , vol. 49, # 33 p. 7337 - 7352
反应条件
sodium hydride 1.) DMF, 25-28 deg C, 45 min; 2.) DMF, 3 h, 30 deg C; Multistep reaction;
参考文献
Mahadevan, Indumathy; Rasmussen, Malcolm
Tetrahedron, 1993 , vol. 49, # 33 p. 7337 - 7352
反应条件
sodium hydride 1.) DMF, 25-28 deg C, 45 min; 2.) DMF, 3 h, 30 deg C; Multistep reaction;
参考文献
Mahadevan, Indumathy; Rasmussen, Malcolm
Tetrahedron, 1993 , vol. 49, # 33 p. 7337 - 7352
反应条件
sodium hydride 1.) DMF, 25-28 deg C, 45 min; 2.) DMF, 3 h, 30 deg C; Multistep reaction;
参考文献
Mahadevan, Indumathy; Rasmussen, Malcolm
Tetrahedron, 1993 , vol. 49, # 33 p. 7337 - 7352
反应条件
romine in dichloromethane T=0 - 20°C; Bromination;
参考文献
Tatsugi, Jiro; Zhiwei, Tong; Amano, Tomohiro; Izawa, Yasuji
Heterocycles, 2000 , vol. 53, # 5 p. 1145 - 1150
