1: 94 percent / aq. HCl / 1 h / Ambient temperature 2: Humicola amino esterase, phosphate buffer, pH 7.5 / Ambient temperature View Scheme

hydrogenchloride 1 h; Ambient temperature;

1: 94 percent / aq. HCl / 1 h / Ambient temperature 2: Humicola amino esterase, phosphate buffer, pH 7.5 / Ambient temperature View Scheme

1: 94 percent / aq. HCl / 1 h / Ambient temperature 2: Humicola amino esterase, phosphate buffer, pH 7.5 / Ambient temperature View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '906717', constants.ctx, '0')">lithium diisopropyl amide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />10&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 98 percent / Et₃N / toluene / Heating<br />2: 85 percent / lithium diisopropylamine / tetrahydrofuran / 10 h / Ambient temperature<br /> <br /> &nbsp;