1-苄基-5-硝基-1H-1,3-苯并咪唑合成路线 （共 4 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 88 h;
参考文献
ARRAY BIOPHARMA, INC.
Patent: WO2008/134354 A1, 2008 ;
Location in patent: Page/Page column 78-79 ;
反应条件
potassium carbonate in butanone 3 h; Heating; Title compound not separated from byproducts.;
参考文献
Benod, Cindy; Subra, Guy; Nahoum, Virginie; Mallavialle, Aude; Guichou, Jean-Francois; Milhau, Julien; Robles, Samuel; Bourguet, William; Pascussi, Jean-Marc; Balaguer, Patrick; Chavanieu, Alain
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3537 - 3549
反应条件
sodium hydride in N,N-dimethyl-formamide T=30°C; 16 h; other 5-substituted benzimidazoles; other alkyl halides; also under neutral conditions; var. solvents; Product distribution;
参考文献
Howell, John R.; Rasmussen, Malcolm
Australian Journal of Chemistry, 1993 , vol. 46, # 8 p. 1177 - 1191
反应条件
ethanol; tin(ll) chloride Heating / reflux;
参考文献
ARRAY BIOPHARMA, INC.
Patent: WO2008/134354 A1, 2008 ;
Location in patent: Page/Page column 79 ;
