(R)-(+)-1-苯基乙醇合成路线 (共 353 条)
反应条件
(S)-2-amino-1,1,3-triphenylpropan-1-ol borane in tetrahydrofuran T=30°C;
参考文献
Yanagi, Takashi; Kikuchi, Ken; Takeuchi, Hideki; Ishikawa, Takehiro; Nishimura, Toshihiro; Kubota, Minoru; Yamamoto, Iwao
Chemical and Pharmaceutical Bulletin, 2003 , vol. 51, # 2 p. 221 - 223
反应条件
titanium(IV) isopropylate in hexane T=-35°C; 3 h;
参考文献
Leven, Matthias; Schloerer, Nils E.; Neudoerfl, Joerg M.; Goldfuss, Bernd
Chemistry - A European Journal, 2010 , vol. 16, # 45 p. 13443 - 13449
反应条件
dimethylsulfide borane complex; diphenyl-N-(3-pyridylmethyl)prolinol N-oxide in tetrahydrofuran 5 h; Heating;
参考文献
O'Neil, Ian A.; Turner, Carl D.; Kalindjian, S. Barret
Synlett, 1997 , vol. 1997, # 7 p. 777 - 780
反应条件
sodium carbonate in toluene T=40°C; 72 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 11-12 p. 828 - 833
反应条件
toluene-4-sulfonic acid in methanol 0.5 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
European Journal of Inorganic Chemistry, , # 6 p. 783 - 788
反应条件
water; potassium carbonate in methanol T=20°C; optical yield given as percent ee;
参考文献
Brondani, Patricia B.; Guilmoto, Nathalie M. A. F.; Andrade, Leandro H.; Dudek, Hanna M.; Fraaije, Marco W.
Tetrahedron, 2012 , vol. 68, # 51 p. 10431 - 10436,6
Title/Abstract Full Text Show Details
Brondani, Patricia B.; Guilmoto, Nathalie M.A.F.; Dudek, Hanna M.; Fraaije, Marco W.; Andrade, Leandro H.
Tetrahedron, 2012 , vol. 68, # 51 p. 10431 - 10436
反应条件
phosphate buffer; lipase T=20°C;
参考文献
Laumen, Kurt; Schneider, Manfred P.
Journal of the Chemical Society, Chemical Communications, 1988 , p. 598 - 600
反应条件
lipase from Burkholderia cepacia (BCL) Enzymatic reaction; optical yield given as percent ee;
参考文献
Gao, Yan; Zhong, Runtao; Qin, Jianhua; Lin, Bingcheng
Chemistry Letters, 2009 , vol. 38, # 3 p. 262 - 263
反应条件
sodium hydroxide; dihydrogen peroxide in diethyl ether T=0 - 20°C; Oxidation;
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9704 - 9710
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 3 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825