(S)-(+)-1-苯基-2-丙醇合成路线 （共 70 条）
反应条件
4 A molecular sieve; chiral diamine; triethylamine in dichloromethane T=-78°C; 3 h; Yield givenYields of byproduct given;
参考文献
Chemistry Letters, , # 3 p. 265 - 266
反应条件
1: triethylamine / CH2Cl2 / 1 h / 0 °C 2: 0.33 g / sodium hydride / dimethylformamide; various solvent(s) / 0.5 h / 0 °C 3: 92 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
1: 0.33 g / sodium hydride / dimethylformamide; various solvent(s) / 0.5 h / 0 °C 2: 92 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 63, # 39 p. 9758 - 9763
反应条件
in benzene T=21°C; 30 h; lipase Amano P/Celite 577; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 53, # 23 p. 5531 - 5534
反应条件
hydrogen cation in water Yield given;
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1330 - 1354
反应条件
potassium carbonate in methanol Ambient temperature;
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600
反应条件
2: K2CO3 / methanol / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , p. 598 - 600
反应条件
1.1: (S,S)-salen-CoIII-OAc / 0.08 h / 0 °C 1.2: 8 h / 0 °C 2.1: sodium tetrahydroborate / ethanol / 2 h / Reflux View Scheme
参考文献
Synthetic Communications, , vol. 41, # 9 p. 1301 - 1308
反应条件
1.1: sodium hydride / dimethyl sulfoxide / 1 h 1.2: 5 h / 25 °C 2.1: (S,S)-salen-CoIII-OAc / 0.08 h / 0 °C 2.2: 8 h / 0 °C 3.1: sodium tetrahydroborate / ethanol / 2 h / Reflux View Scheme
参考文献
Synthetic Communications, , vol. 41, # 9 p. 1301 - 1308
反应条件
1: lipase from candida antartica / aq. phosphate buffer / 48 h / 30 °C 2: sodium hydroxide; water / 2 h / 20 °C View Scheme
参考文献
Letters in Organic Chemistry, , vol. 9, # 9 p. 615 - 621
