Cbz-val-try甲酯合成路线 （共 9 条）
反应条件
1: aqueous methanol. NaOH 2: HBr; acetic acid View Scheme
参考文献
Schwyzer et al.
Helvetica Chimica Acta, 1958 , vol. 41, p. 1273,1280
反应条件
triethylamine; BETAMETHASONE SODIUM PHOSPHATE in N,N-dimethyl-formamide
3 h; Ambient temperature;
参考文献
Kim, Sunggak; Chang, Heung; Ko, Young Kwan
Tetrahedron Letters, 1985 , vol. 26, # 10 p. 1341 - 1342
反应条件
triethylamine; 2-Pyridon-1-yl diphenyl phosphate in N,N-dimethyl-formamide
3 h; Ambient temperature;
参考文献
Kim, Sunggak; Kim, Sung Soo
Journal of the Chemical Society, Chemical Communications, 1986 , # 9 p. 719
反应条件
Amberlyst 15
T=60°C; 2 h;
参考文献
Greenlee, William J.; Thorsett, Eugene D.
Journal of Organic Chemistry, 1981 , vol. 46, p. 5351 - 5353
反应条件
hydrogenchloride in methanol
T=20°C; 24 h;
参考文献
Stark, Timo; Hofmann, Thomas
Journal of Agricultural and Food Chemistry, 2005 , vol. 53, # 18 p. 7222 - 7231
反应条件
tetrahydrofuran; tributyl-amine; chloroformic acid ethyl ester
anschliessend Behandeln mit L-Tyrosin-methylester-hydrochlorid und Triaethylamin in Dioxan;
参考文献
Schwarz et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 5697,5701
反应条件
diethyl aminoacetic acid ethylester in chloroform; N,N-dimethyl-formamide
参考文献
Sakakibara; Ito
Bulletin of the Chemical Society of Japan, 1967 , vol. 40, # 3 p. 656 - 661
反应条件
watersoluble carbodiimide; benzotriazol-1-ol; triethylamine
T=0°C; 18 h; Yield given;
参考文献
Abiko; Onodera; Sekino
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 8 p. 2507 - 2511
反应条件
ammonia
1.) chloroform, 15 min; 2.) dioxane, room temp., 48 h; Yield given. Multistep reaction;
参考文献
Martynov, V. F.; Anokhina, V. V.; Belokrylov, G. A.; Leont'eva, L. I.; Sorochinskaya, E. I.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 10 p. 2369 - 2377,2122 - 2128
