2,2-二甲基-N-[2-甲基-3-(三氟甲基)苯基]-丙酰胺合成路线 （共 5 条）
反应条件
n-butyllithium 1.) ether, hexane, 4 h, 2.) ether, hexane, overnight; Yield given. Multistep reaction;
参考文献
The Trustees of Princeton University
Patent: US5248781 A1, 1993 ;
反应条件
1: 93 percent / K2CO3 / acetone / 6 h / Heating 2: 1.) BuLi / 1.) ether, hexane, 4 h, 2.) ether, hexane, overnight View Scheme
参考文献
Jaouhari, Rabih; Quinn, Philip
Heterocycles, 1994 , vol. 38, # 10 p. 2243 - 2246
反应条件
1: 93 percent / K2CO3 / acetone / 6 h / Heating 2: 1.) BuLi / 1.) ether, hexane, 4 h, 2.) ether, hexane, overnight View Scheme
参考文献
Jaouhari, Rabih; Quinn, Philip
Heterocycles, 1994 , vol. 38, # 10 p. 2243 - 2246
反应条件
hydrogenchloride in ethanol
反应条件
1: 78.3 percent / KOH / ethane-1,2-diol / 8 h / 160 °C 2: 86 percent / ethane-1,2-diol / 6 h / 160 °C 3: 90 percent / KOH / methanol / 3 h / Heating View Scheme
参考文献
Jaouhari, Rabih; Quinn, Philip
Heterocycles, 1994 , vol. 38, # 10 p. 2243 - 2246
