1,1,1,3,4,4-六氟-2-(三氟甲基)-3-丁烯-2-醇合成路线 （共 5 条）
反应条件
1: 1,1-dibromo-1,2,2,2-tetrafluoroethane With zinc in DMF (N,N-dimethyl-formamide) T=80 - 95°C; 6.5 h; 2: 1,1,1,3,3,3-hexafluoro-2-propanone T=20°C;
参考文献
Daikin Industries, Ltd.
Patent: EP1415974 A1, 2004 ;
Location in patent: Page 102 ;
反应条件
in diethyl ether reaction at -70°C, 2 hours;;
参考文献
Gmelin Handbook: F: PerFHalOrg.4, 2.2.4, page 68 - 115
反应条件
n-butyllithium in diethyl ether
参考文献
Tarrant,P. et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 2742 - 2745
反应条件
in diethyl ether reaction at -78°C, warming to 20°C;; yield depending on method of isolation;;
参考文献
Drakesmith,F.G. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 1 p. 286 - 291
反应条件
(i) MeLi, Et2O, (ii) /BRN= 607236/; Multistep reaction;
参考文献
Chang,I.S. et al.
Canadian Journal of Chemistry, 1972 , vol. 50, p. 512 - 520
