1: With sodium carbonate; ozone in dichloromethane
T=-78°C;
2: With acetic anhydride; triethylamine in dichloromethane
T=0 - 20°C;
参考文献
Gorczynski, Michael J.; Smitherman, Pamela K.; Akiyama, Taro E.; Wood, Harold B.; Berger, Joel P.; King, S. Bruce; Morrow, Charles S.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 15 p. 4631 - 4639
1: CDDE With ozone in methanol; dichloromethane
T=-40°C;
2: With toluene-4-sulfonic acid in methanol
T=20°C; 1.5 h;
3: methanol With dimethylsulfide; sodium hydrogencarbonate
T=20°C;
参考文献
Cryle, Max J.; Ortiz De Montellano, Paul R.; De Voss, James J.
Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2455 - 2469
