1-(2,5-二甲基-1H-吡咯-3-基)-乙酮合成路线 （共 10 条）
反应条件
ammonium chloride; palladium dichloride in ethanol T=50 - 55°C; Glaser coupling reaction; 5 h;
参考文献
Vizer; Yerzhanov; Dembitsky
Heteroatom Chemistry, 2006 , vol. 17, # 1 p. 66 - 73
反应条件
Cu2Cl2; air; ammonium chloride in ethanol T=50 - 60°C; 2 h;
参考文献
Vizer; Dedeshko; Erzhanov
Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 5 p. 616 - 617
反应条件
1: 77 percent / molecular sieves 4 Angstroem / tetrahydrofuran / 168 h / 20 °C 2: 57 percent / Pd(PPh3)4; K2CO3; mesityl bromide / dimethylformamide / 3.5 h / 150 °C View Scheme
参考文献
Aoyagi, Yutaka; Mizusaki, Toshihiko; Shishikura, Masahiro; Komine, Takashi; Yoshinaga, Tokuji; Inaba, Haruko; Ohta, Akihiro; Takeya, Koichi
Tetrahedron, 2006 , vol. 62, # 36 p. 8533 - 8538
反应条件
ammonia T=110 - 115°C;
参考文献
Magnanini; Bentivoglio
Gazzetta Chimica Italiana, 1894 , vol. 24 I, p. 436
参考文献
Magnanini
Gazzetta Chimica Italiana, 1893 , vol. 23 I, p. 463
反应条件
water 1.) CH2Cl2, -50 deg C, 20 min, 2.) CH2Cl2, 20 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Pindur, U.; Flo, C.
Journal of Heterocyclic Chemistry, 1989 , vol. 26, p. 1563 - 1568
反应条件
diethyl ether; magnesium und Erwaermen des Reaktionsprodukts mit Acetylchlorid;
参考文献
Oddo; Acuto
Gazzetta Chimica Italiana, 1935 , vol. 65, p. 1029,1034
反应条件
T=100°C; im geschlossenen Rohr;
参考文献
Magnanini
Gazzetta Chimica Italiana, 1893 , vol. 23 I, p. 463
Full Text Show Details
Magnanini; Scheidt
Gazzetta Chimica Italiana, 1892 , vol. 22 I, p. 444
Full Text Show Details
Magnanini
Gazzetta Chimica Italiana, 1889 , vol. 19, p. 281
参考文献
Magnanini; Bentivoglio
Gazzetta Chimica Italiana, 1894 , vol. 24 I, p. 436
参考文献
Magnanini
Gazzetta Chimica Italiana, 1893 , vol. 23, # 1 p. 465
