4-甲氧基-3-三氟甲基苯硼酸合成路线 (共 2 条)
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.333333 h; 2: With tri-isopropoxy-borane in tetrahydrofuran; hexane T=-78 - 20°C; 3: With water; acetic acid in tetrahydrofuran; hexane T=20°C;
参考文献
WO2007/39470 A1, ;
Page/Page column 29 ;
WO 2007/039470 A1
反应条件
1: 4-bromo-1-methoxy-2-(trifluoromethyl)benzene With n-butyllithium in tetrahydrofuran; hexanes T=-78°C; 0.333333 h; 2: tri-isopropoxy-borane in tetrahydrofuran; hexanes T=-78°C; 0.5 h; 3: With acetic acid in tetrahydrofuran; hexanes; water T=20°C;
参考文献
US2007/111992 A1, ;
Page/Page column 15-16 ;
US 20070111992 A1