1-甲基-1,3-环己二烯合成路线 （共 28 条）
反应条件
potassium tert-butylate in tert-butyl alcohol
T=80°C; 6 h;
参考文献
Sellen, Mikael; Baeckvall, Jan-E.; Helquist, Paul
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 835 - 839
反应条件
(i) TsNHNH2, TsOH, THF, (ii) MeLi, benzene, Et2O; Multistep reaction;
参考文献
Birch,A.J.; Rao,G.S.R.S.
Australian Journal of Chemistry, 1970 , vol. 23, p. 1641 - 1649
反应条件
1: 57.8 g / aq. HCl / tetrahydrofuran / 15 h / 20 °C
2: MeLi / diethyl ether / 15 h / 0 °C
View Scheme
参考文献
Liu, Chunjian; Bao, Guanglin; Burnell, D. Jean
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 20 p. 2644 - 2656
反应条件
1: 95 percent / CuI
2: potassium tert-butoxide / 2-methyl-propan-2-ol / 6 h / 80 °C
View Scheme
参考文献
Sellen, Mikael; Baeckvall, Jan-E.; Helquist, Paul
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 835 - 839
反应条件
1: 1.) n-BuLi / 1.) THF, -70 degC, 15 min 2.) 1 h
2: 73 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 6 h / 80 °C
View Scheme
参考文献
Sellen, Mikael; Baeckvall, Jan-E.; Helquist, Paul
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 835 - 839
反应条件
1: 90 percent / dimethylformamide / 24 h / 0 °C
2: 1.) n-BuLi / 1.) THF, -70 degC, 15 min 2.) 1 h
3: 73 percent / potassium tert-butoxide / 2-methyl-propan-2-ol / 6 h / 80 °C
View Scheme
参考文献
Sellen, Mikael; Baeckvall, Jan-E.; Helquist, Paul
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 835 - 839
反应条件
sodium isopropanolate in various solvent(s)
Yield given. Yields of byproduct given;
参考文献
Baeckvall, Jan-E.; Bystroem, Styrbjoern E.; Nordberg, Ruth E.
Journal of Organic Chemistry, 1984 , vol. 49, # 24 p. 4619 - 4631
反应条件
copper(II) sulfate
Erhitzen unter Abspaltung von Wasser;
参考文献
Birch
Journal of the Chemical Society, 1947 , p. 1642,1647
反应条件
pentacarbonyliron(0); ammonium cerium(IV) nitrate; ammonia; lithium; tert-butyl alcohol
2.) n-Bu2O; 3.) pentane; Multistep reaction;
参考文献
Ingham; Johnson; Sadler; Nairn
Journal of Organometallic Chemistry, 1997 , vol. 531, # 1-2 p. 237 - 242
参考文献
Parsons, E. J.; Jennings, P. W.
Organometallics, 1988 , vol. 7, p. 1435 - 1437
