N-chloro-succinimide; trifluorormethanesulfonic acid; palladium diacetate in 1,2-dichloro-ethane T=20°C; 10 h; Sealed tube; regioselective reaction;

1: potassium carbonate / acetonitrile / 4 h / |Reflux; |Sealed tube 2: N-chloro-succinimide; palladium diacetate; sodium pyrosulphate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C / |Sealed tube 3: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

1: N-chloro-succinimide; palladium diacetate; sodium pyrosulphate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C / |Sealed tube 2: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

1: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 11 h / 20 °C / |Sealed tube 2: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

1: potassium carbonate / acetonitrile / 2 h / |Reflux; |Sealed tube 2: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 11 h / 20 °C / |Sealed tube 3: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

1: potassium carbonate / acetonitrile / 2 h / |Reflux; |Sealed tube 2: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

1.1: tert.-butyl lithium / diethyl ether / 3.75 h / 0 °C / |Sealed tube 1.2: 0 - 20 °C / |Sealed tube 2.1: potassium carbonate / acetonitrile / 4 h / |Reflux; |Sealed tube 3.1: N-chloro-succinimide; palladium diacetate; sodium pyrosulphate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C / |Sealed tube 4.1: N-chloro-succinimide; palladium diacetate; trifluorormethanesulfonic acid / 1,2-dichloro-ethane / 10 h / 20 °C / |Sealed tube View Scheme

hydrazine hydrate T=60°C; 2 h; Sealed tube; regioselective reaction;