4-苯甲氧基苯(甲)酰氯合成路线 （共 47 条）
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane T=23°C; 2 h;
参考文献
Cowart, Marlon; Faghih, Ramin; Curtis, Michael P.; Gfesser, Gregory A.; Bennani, Youssef L.; Black, Lawrence A.; Pan, Liping; Marsh, Kennan C.; Sullivan, James P.; Esbenshade, Timothy A.; Fox, Gerard B.; Hancock, Arthur A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 38 - 55
反应条件
in 1,4-dioxane; N-methyl-acetamide
参考文献
Sterling Winthrop Inc.
Patent: US5618528 A1, 1997 ;
反应条件
oxalyl dichloride in dichloromethane T=0°C; Heating / reflux;
参考文献
WO2004/50657 A2, ;
Page 38-39 ;
WO 2004/050657 A2
反应条件
1: 75 percent / potassium carbonate, sodium iodide / acetonitrile / Heating 2: 78 percent / 2M aq. sodium hydroxide / ethanol / 6 h / Heating 3: 77 percent / thionyl chloride View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 825 - 831
反应条件
1: sodium methylate 2: methanolic KOH-solution 3: benzene; phosphorus pentachloride View Scheme
参考文献
Journal of the Chemical Society, , vol. 97, p. 1747
反应条件
1: KOH / H2O; ethanol / 6 h / Heating 2: oxalyl chloride / CH2Cl2 / 8 h / 20 °C View Scheme
参考文献
British Journal of Pharmacology, , vol. 142, # 5 p. 811 - 820
反应条件
1: aq. NaOH 2: (COCl)2; DMF / CH2Cl2 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 15 p. 2031 - 2034
参考文献
Wako Pure Chemical Industries, Ltd.; Nippon Telegraph and Telephone Corporation
Patent: US5114615 A1, 1992 ;
反应条件
1: 1.) K2CO3, KI; 2.) NaOH / 1.) DMF 2: SOCl2 / dimethylformamide / 0.5 h / 60 °C View Scheme
参考文献
Phytochemistry (Elsevier), , vol. 19, p. 2179 - 2184
