(4-氨基-3-甲氧基苯基)甲醇合成路线 (共 4 条)
反应条件
hydrazine hydrate; palladium on activated charcoal in methanol 1.75 h; Heating;
参考文献
Garcia, C.; Malthete, J.; Collet, A.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, # 1 p. 93 - 95
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C;
参考文献
Zhang, Qin; Zhong, Ying; Yan, Lin-Na; Sun, Xun; Gong, Tao; Zhang, Zhi-Rong
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 3 p. 1010 - 1014
反应条件
1: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 0 - 20 °C 2: hydrogen / Raney nickel / methanol / 16 h / 20 °C View Scheme
参考文献
ABBVIE INC.; Vasudevan, Anil; Penning, Thomas Dale; Chen, Huanming; Liang, Bo; Wang, Shaohui; Zhao, Zhongqiang; Chai, Dikun; Yang, Leifu; Gao, Yingxiang; Pliushchev, Marina
Patent: US2014/171429 A1, 2014 ;
反应条件
manganese(IV) oxide in tetrahydrofuran
3 h; Reflux;
参考文献
Zhang, Qin; Zhong, Ying; Yan, Lin-Na; Sun, Xun; Gong, Tao; Zhang, Zhi-Rong
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 3 p. 1010 - 1014