3，6-二乙酰基-N-乙基咔唑合成路线 （共 11 条）
反应条件
potassium hydroxide; water; potassium hexacyanoferrate(III)
参考文献
Buu-Hoi; Royer
Journal of Organic Chemistry, 1950 , vol. 15, p. 123,127
反应条件
1: With AlCl3, aluminium chloride in dichloromethane
T=0 - 20°C; 7 h;
2: With water in dichloromethane
T=0°C;
参考文献
Lee, Keon-Woo; Cho, Chang-Ho; Min, Kyoung-Hoon; Kharbash, Raisa; Lee, Chang-Soon; Kim, Sung-Hyun
Patent: US2010/145068 A1, 2010 ;
Location in patent: Page/Page column 7 ;
反应条件
carbon disulfide; AlCl3, aluminium chloride
Friedel-Crafts Acylation; 3 h; Cooling with iceReflux;
参考文献
Asker, Erol; Filiz, Fahrettin
Journal of Molecular Structure, 2013 , vol. 1040, p. 65 - 74
反应条件
n-butyllithium in tetrahydrofuran
参考文献
Park, Minnie; Buck, Jason R.; Rizzo, Carmelo J.
Tetrahedron, 1998 , vol. 54, # 42 p. 12707 - 12714
反应条件
1: 70 percent / Br2, acetic acid / 0.33 h / Ambient temperature
2: n-Buli / tetrahydrofuran
View Scheme
参考文献
Park, Minnie; Buck, Jason R.; Rizzo, Carmelo J.
Tetrahedron, 1998 , vol. 54, # 42 p. 12707 - 12714
反应条件
1: NaOH / acetone / 4 h / Ambient temperature
2: n-Buli / tetrahydrofuran
View Scheme
参考文献
Park, Minnie; Buck, Jason R.; Rizzo, Carmelo J.
Tetrahedron, 1998 , vol. 54, # 42 p. 12707 - 12714
反应条件
sodium hydroxide; water; acetone
参考文献
Gilman; Kirby
Journal of Organic Chemistry, 1936 , vol. 1, p. 146,152
反应条件
1: acetone; aqueous KOH-solution
2: aluminium chloride; carbon disulfide
View Scheme
参考文献
Buu-Hoi; Royer
Recueil des Travaux Chimiques des Pays-Bas, 1947 , vol. 66, p. 533,541
反应条件
carbon disulfide; aluminium trichloride
参考文献
Buu-Hoi; Royer
Recueil des Travaux Chimiques des Pays-Bas, 1947 , vol. 66, p. 533,541
反应条件
AlCl3, aluminium chloride
Friedel Crafts acylation;
参考文献
Tang, Huaijun; Zhang, Zhiguo; Cong, Changjie; Zhang, Keli
Russian Journal of Organic Chemistry, 2009 , vol. 45, # 4 p. 559 - 563
