1-丁烷-2-基-2,4-二甲基苯合成路线 （共 12 条）
反应条件
potassium fluoride; jackiePhos; copper(l) chloride; bis(dibenzylideneacetone)-palladium(0) in acetonitrile T=60°C; 18 h; Inert atmosphereSchlenk technique;
参考文献
Li, Ling; Wang, Chao-Yuan; Huang, Rongcai; Biscoe, Mark R.
Nature Chemistry, 2013 , vol. 5, # 7 p. 607 - 612
反应条件
CuCN in tetrahydrofuran 1.)s-BuLi, CuCN, -78 deg C, then -20 deg C, 2.) -70 deg C, aryl triflate, then -20 deg C, 40h;
参考文献
Mc Murry, John E.; Mohanraj, Subramaniam
Tetrahedron Letters, 1983 , vol. 24, # 27 p. 2723 - 2726
反应条件
in m-xylene T=80°C; 4 h;
参考文献
Nitta, Yoshihiro; Arakawa, Yasushi; Ueyama, Naoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2710 - 2718
反应条件
CuCN in tetrahydrofuran 1.)s-BuLi, CuCN, -78 deg C, then -20 deg C, 2.) -70 deg C, aryl triflate, then -20 deg C, 40h;
参考文献
Mc Murry, John E.; Mohanraj, Subramaniam
Tetrahedron Letters, 1983 , vol. 24, # 27 p. 2723 - 2726
参考文献
Nightingale; Radford; Shanholtzer
Journal of the American Chemical Society, 1942 , vol. 64, p. 1662,1665
反应条件
diethyl ether Behandlung des erhaltenen Alkohols mit Acetanhydrid und konz. H2SO4 und Hydrierung des Reaktionsprodukts an Raney-Nickel in Methanol bei 80-90grad/140 at;
参考文献
Nightingale; Radford; Shanholtzer
Journal of the American Chemical Society, 1942 , vol. 64, p. 1662,1665
反应条件
in m-xylene 5 h; Heating;
参考文献
Nitta, Yoshihiro; Arakawa, Yasushi; Ueyama, Naoto
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 7 p. 2710 - 2718
参考文献
Hickinbottom; Rogers
Journal of the Chemical Society, 1957 , p. 4124,4129
参考文献
Hickinbottom; Rogers
Journal of the Chemical Society, 1957 , p. 4124,4129
参考文献
Nightingale; Taylor; Smelser
Journal of the American Chemical Society, 1941 , vol. 63, p. 258,260
