6-(氯甲酸基)己炔羧酸乙酯合成路线 （共 21 条）
反应条件
thionyl chloride in dichloromethane T=50°C; 2 h;
参考文献
Shiraishi; Kato; Terao; Ashida; Terashita; Kito
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2214 - 2221
反应条件
oxalyl dichloride in benzene T=0°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 54, # 21 p. 5126 - 5128
Monatshefte fur Chemie, , vol. 135, # 5 p. 519 - 541
反应条件
1: 80 percent / KOH / ethanol / 16 h / 50 °C 2: oxalyl chloride / benzene / 1 h / 0 °C View Scheme
参考文献
Monatshefte fur Chemie, , vol. 135, # 5 p. 519 - 541
反应条件
1: H2SO4 2: SOCl2 / 30 °C View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. <4>7, p. 219
反应条件
1: SnCl4 / 1,2-dichloro-ethane / 1 h / Ambient temperature 2: H2NNH2*H2O, KOH / various solvent(s) / 4 h / 210 °C View Scheme
参考文献
Labaudiniere, Richard; Hilboll, Gerd; Leon-Lomeli, Alicia; Terlain, Bernard; Cavy, Francoise; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 17 p. 3170 - 3179
反应条件
1: AlCl3 / 2 h / 90 °C 2: NaBH4 / methanol / 0.5 h / 0 °C 3: 95 percent / 2.5 N NaOH / tetrahydrofuran / 3 h / 70 °C 4: boron trifluoride etherate / toluene / 2 h / 60 °C View Scheme
参考文献
Shiraishi; Kato; Terao; Ashida; Terashita; Kito
Journal of Medicinal Chemistry, 1989 , vol. 32, # 9 p. 2214 - 2221
反应条件
1: aluminium chloride; carbon disulfide / Behandeln des Reaktionsgemisches mit wss. Salzsaeure 2: aq.-ethanolic KOH-solution View Scheme
参考文献
Cagniant; Cagniant
Bulletin de la Societe Chimique de France, 1954 , p. 1349,1353
反应条件
1: 1.) Zn-Cu 2: hydrolyze View Scheme
参考文献
Tahara, Satoshi; Hosokawa, Keizo; Mizutani, Junya
Agricultural and Biological Chemistry, 1980 , vol. 44, # 1 p. 193 - 198
参考文献
Knox, Graham R.; Thom, Ian G.
Journal of the Chemical Society, Chemical Communications, 1981 , # 8 p. 373 - 374
反应条件
copper; zinc Multistep reaction;
参考文献
Tahara, Satoshi; Hosokawa, Keizo; Mizutani, Junya
Agricultural and Biological Chemistry, 1980 , vol. 44, # 1 p. 193 - 198
