6-溴-1H-吲哚-1-羧酸叔丁酯合成路线 （共 5 条）
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran T=20°C; 4 h;
参考文献
Torraca; Huang; Parrish; Buchwald
Journal of the American Chemical Society, 2001 , vol. 123, # 43 p. 10770 - 10771
反应条件
tris-(dibenzylideneacetone)dipalladium(0); t-Bu Brett Phos; tri-isobutyl aluminium; butanone; potassium bromide in toluene T=100°C; 24 h; Inert atmosphere;
参考文献
Shen, Xiaoqiang; Hyde, Alan M.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14076 - 14078
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in N,N-dimethyl-formamide T=0 - 20°C; 1 h;
参考文献
Herdemann, Matthias; Weber, Alexander; Jonveaux, Jerome; Schwoebel, Frank; Stoeck, Michael; Heit, Isabelle
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1852 - 1856
反应条件
1: KOAc; PdCl2(dppf) / dioxane / 48 h / 100 °C 2: 11 percent / K3PO4; PdCl2(dppf) / dioxane / 72 h / 100 °C View Scheme
参考文献
Prieto, Monica; Zurita, Esther; Rosa, Esmeralda; Munoz, Lourdes; Lloyd-Williams, Paul; Giralt, Ernest
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6812 - 6820
反应条件
tri-isopropoxy-borane; lithium diisopropyl amide in tetrahydrofuran T=0°C; 2 h; Inert atmosphere;
参考文献
Herdemann, Matthias; Weber, Alexander; Jonveaux, Jerome; Schwoebel, Frank; Stoeck, Michael; Heit, Isabelle
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 6 p. 1852 - 1856
