顺-1,4-二氯-2-丁烯合成路线 （共 65 条）
反应条件
lithium hydride
1) DMF, 0 deg C, 2 h, 2) r.t., 60 h; Yield given. Multistep reaction;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
(i) NaH, THF, (ii) nBuLi, hexane, (iii) /BRN= 1719692/; Multistep reaction;
参考文献
Sum,P.-E.; Weiler,L.
Canadian Journal of Chemistry, 1977 , vol. 55, p. 996 - 1000
反应条件
air; silica gel; triethylamine
0.05 h; microwave irradiation;
参考文献
Aydogan, Feray; Basarir, Mehmet; Yolacan, Cigdem; Demir, Ayhan S.
Tetrahedron, 2007 , vol. 63, # 39 p. 9746 - 9750
反应条件
potassium bromide in N,N-dimethyl-formamide
T=60°C; 20 h;
参考文献
Yang, Donglai; Arifhodzic, Lejla; Ganellin, C. Robin; Jenkinson, Donald H.
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 907 - 923
反应条件
N,O-bis-(trimethylsilyl)-acetamide; ammonium hypophosphorous acid
T=110°C; 72 h; Inert atmosphere;
参考文献
Pav, Ondrej; Zbornikova, Eva; Budesinsky, Milos; Rosenberg, Ivan
Tetrahedron, 2013 , vol. 69, # 43 p. 9120 - 9129
