顺-1,4-二氯-2-丁烯合成路线 （共 65 条）
反应条件
potassium carbonate in methanol
T=25°C; 96 h; Yield given. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
potassium carbonate in methanol
T=25°C; 96 h; Yield given. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
lithium hydride
1) DMF, 0 deg C, 2) r.t., 96 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
参考文献
Reppe et al.
Justus Liebigs Annalen der Chemie, 1955 , vol. 596, p. 1,95,131
反应条件
in N,N-dimethyl-formamide
T=20°C; Inert atmosphere;
参考文献
Worthy, Amanda D.; Joe, Candice L.; Lightburn, Thomas E.; Tan, Kian L.
Journal of the American Chemical Society, 2010 , vol. 132, # 42 p. 14757 - 14759
反应条件
potassium carbonate; potassium iodide in N,N-dimethyl-formamide
T=20°C;
参考文献
Bojarski, Andrzej J.; Duszynska, Beata; Kolaczkowski, Marcin; Kowalski, Piotr; Kowalska, Teresa
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5863 - 5866
反应条件
potassium hydroxide in methanol; N,N-dimethyl-formamide
0.25 h; Heating;
参考文献
Malhas, Rana N.; Ibrahim, Yehia A.
Synthesis, 2006 , # 19 p. 3261 - 3269
反应条件
methanol-d4; ozone
1.)-40 deg C, 2.) ether, -80 deg C, 2 d; Yield given. Multistep reaction;
参考文献
Griesbaum, Karl; Meister, Martin
Chemische Berichte, 1985 , vol. 118, # 2 p. 845 - 850
反应条件
in ethanol
P=12751 Torr; 3 h; -50 deg C to room temp.;
参考文献
Mahboobi, Siavosh; Fischer, Erich Chr.; Eibler, Ernst; Wiegrebe, Wolfgang
Archiv der Pharmazie (Weinheim, Germany), 1988 , vol. 321, p. 423 - 424
反应条件
n-butyllithium in tetrahydrofuran
1.) -70 degC, 3.5h, 2.) room temperature, 16.5h;
参考文献
Ogura, K.; Yamashita, M.; Suzuki, M.; Furukawa, S.; Tsuchinashi, G.
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 6 p. 1637 - 1642
