顺-1,4-二氯-2-丁烯合成路线 （共 65 条）
参考文献
Curators of the University of Missouri; 3M Innovative Properties Company
Patent: US6458865 B2, 2002 ;
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride T=25°C; 14 h; Yield given. Yields of byproduct given;
参考文献
Depres, Jean-Pierre; Greene, Andrew E.
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 928 - 931
反应条件
1: in dichloromethane T=5 - 20°C; 24.1667 h; 2: With hydrogenchloride in dichloromethane; water T=0°C;
参考文献
LABORATORIOS DEL DR. ESTEVE, S.A.
Patent: EP1849772 A1, 2007 ;
Location in patent: Page/Page column 18 ;
反应条件
1: carbamic acid 1,1-dimethylethyl ester With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.166667 h; 2: (Z)-1,4-Dichloro-2-butene in N,N-dimethyl-formamide T=20 - 65°C; 20.25 h;
参考文献
Laboratorios del Dr. Esteve S.A.
Patent: EP1849781 A1, 2007 ;
Location in patent: Page/Page column 89 ;
反应条件
sodium hydride in N,N-dimethyl-formamide T=20 - 50°C; 5.66667 h;
参考文献
Tsuzuki, Yasunori; Chiba, Katsumi; Mizuno, Kazuhiro; Tomita, Kyoji; Suzuki, Kenji
Tetrahedron Asymmetry, 2001 , vol. 12, # 21 p. 2989 - 2997
反应条件
potassium carbonate in methanol Delepine reactions;
参考文献
Rajesh, Tammana; Rao, Sambangi Polinaini Narayana; Suresh, Kopparthi; Madhusudhan, Gutta; Mukkanti, Kagga
Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 6 p. 1392 - 1397
反应条件
air; silica gel; triethylamine 0.0666667 h; microwave irradiation;
参考文献
Aydogan, Feray; Basarir, Mehmet; Yolacan, Cigdem; Demir, Ayhan S.
Tetrahedron, 2007 , vol. 63, # 39 p. 9746 - 9750
反应条件
maleic anhydride in acetone 4 h; IrradiationInert atmosphere;
参考文献
Pares, Sonia; De March, Pedro; Font, Josep; Alibes, Ramon; Figueredo, Marta
European Journal of Organic Chemistry, 2011 , # 20-21 p. 3888 - 3895
反应条件
ammonia in ethanol; water T=100°C; 5 h;
参考文献
Palmer, Brian D; Denny, William A
Synthetic Communications, 1987 , vol. 17, # 5 p. 601 - 610
反应条件
Grubb's 2nd generation catalyst in dichloromethane 12 h; Heating;
参考文献
Advanced Synthesis and Catalysis, , vol. 344, # 6-7 p. 634 - 637
