N-(1-苄基哌啶-4-基)-N-苯基丙酰胺合成路线 (共 6 条)
反应条件
1: hydrogen; palladium 10 on activated carbon / methanol; acetic acid / 50 °C 2: potassium carbonate; tetrabutylammomium bromide / acetonitrile View Scheme
参考文献
Gupta, Pradeep Kumar; Yadav, Shiv Kumar; Bhutia, Yangchen Doma; Singh, Poonam; Rao, Pooja; Gujar, Niranjan Laxman; Ganesan, Kumaran; Bhattacharya, Rahul
Medicinal Chemistry Research, 2013 , vol. 22, # 8 p. 3888 - 3896
反应条件
1: With palladium on activated charcoal; hydrogen 2: With hydrogenchloride in water
参考文献
Schoenberger, Matthias; Trauner, Dirk
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3264 - 3267
Angew. Chem., 2014 , vol. 53-126, # 12 p. 3329 - 3332
反应条件
1: 95 percent / H2, conc. HCl / 10 percent Pd/C / ethanol / 50 °C / 2068.6 Torr 2: 7 h / 100 °C View Scheme
参考文献
Brine; Boldt; Huang; Sawyer; Carroll
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 677 - 686
反应条件
2: Na2CO3 3: KOH / 2-methyl-propan-2-ol / 1) 25 degC, 2h, 2) 65-70 degC, 7h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 13 p. 2138 - 2140
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in ethanol T=50°C; P=2068.6 Torr;
参考文献
Brine; Boldt; Huang; Sawyer; Carroll
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 677 - 686
反应条件
1: 95 percent / H2, conc. HCl / 10 percent Pd/C / ethanol / 50 °C / 2068.6 Torr 2: 2) HCl / 1) CH2Cl2, 2) diethyl ether View Scheme
参考文献
Brine; Boldt; Huang; Sawyer; Carroll
Journal of Heterocyclic Chemistry, 1989 , vol. 26, # 3 p. 677 - 686