反应条件
1: 46.9 g / ethanol / 1 h / Ambient temperature 2: 1.) NaH / 1.) DMF, 30 min, 2.) DMF, RT, 2 h 3: 277 mg / DIBAL-H / toluene / 1 h / -74 °C 4: 71.2 percent / 4-methylmorpholine-N-oxide, tetrapropyl-ammonium perruthenate, molecular sieves 4 Angstroem / CH2Cl2 / 2 h 5: 71.3 percent / acetonitrile / 14 h / Heating View Scheme
参考文献
Watanabe, Masamichi; Koike, Haruo; Ishiba, Teruyuki; Okada, Tetsuo; Seo, Shujiro; Hirai, Kentaro
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 2 p. 437 - 444
