2,2,4-三甲基-1,2-二氢喹啉合成路线 （共 35 条）
参考文献
Schlenk; Bergmann
Justus Liebigs Annalen der Chemie, 1928 , vol. 463, p. 208
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Reddelien; Thurm
Chemische Berichte, 1932 , vol. 65, p. 1514
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Knoevenagel
Chemische Berichte, 1922 , vol. 55, p. 2318
参考文献
DE363582 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 520
Chemische Berichte, , vol. 55, p. 1922
参考文献
Journal of the American Chemical Society, , vol. 60, p. 1458,1464
参考文献
Journal of the American Chemical Society, , vol. 60, p. 1458,1464
参考文献
Chemische Berichte, , vol. 65, p. 1514
DE365582 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 520
Chemische Berichte, , vol. 55, p. 1926
参考文献
Chemische Berichte, , vol. 65, p. 1514
DE365582 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 520
Chemische Berichte, , vol. 55, p. 1926
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide T=40 - 60°C; 8 h;
参考文献
Shikhaliev, Kh. S.; Shmyreva, Zh. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , vol. 24, # 8 p. 898 - 900
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , # 8 p. 1091 - 1093
反应条件
1.1: 71 percent / KOH / dimethylsulfoxide / 0.5 h
2.1: LiClO4; bis(2,2,2-trichloroethyl) azodicarboxylate / diethyl ether / 0 - 55 °C
2.2: 51 percent / Zn; AcOH / acetone / 3 h / 20 °C
View Scheme
参考文献
Brown, Chad W.; Liu, Shengquan; Klucik, Jozef; Berlin, K. Darrell; Brennan, Patrick J.; Kaur, Devinder; Benbrook, Doris M.
Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 1008 - 1017
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide
T=40 - 60°C; 5 h;
参考文献
Shikhaliev, Kh. S.; Shmyreva, Zh. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988 , vol. 24, # 8 p. 898 - 900
Khimiya Geterotsiklicheskikh Soedinenii, 1988 , # 8 p. 1091 - 1093
参考文献
Levin; Nekipelova; Khodot
Russian Chemical Bulletin, 2005 , vol. 54, # 10 p. 2312 - 2316
