(3aR,6aR)-5-[(4R)-2,2-二甲基-1,3-二氧戊环-4-基]-2,2-二甲基-3A,6A-二氢呋喃并[2,3-d][1,3]二氧杂环戊烯-6-基乙酸酯合成路线 （共 7 条）
反应条件
pyridine T=60°C; 14 h;
参考文献
Raju, Ravinder; Castillo, Bernard F.; Richardson, Stewart K.; Thakur, Meena; Severins, Ryan; Kronenberg, Mitchell; Howell, Amy R.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4122 - 4125
反应条件
in pyridine T=75°C; 16 h;
参考文献
Schmid, Walther; Zbiral, Erich
Monatshefte fuer Chemie, 1983 , vol. 114, p. 1253 - 1258
反应条件
1: PCC, molecular sieves / CH2Cl2 2: pyridine View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 10, # 10 p. 1855 - 1859
反应条件
pyridine T=80°C; Acetylation; 6 h;
参考文献
Tetrahedron Letters, , vol. 40, # 28 p. 5191 - 5192
反应条件
1.1: sulfuric acid / 10 h / 0 - 20 °C 2.1: dipyridinium dichromate; acetic anhydride / dichloromethane / 3 h / Reflux 3.1: diethyl ether; water / 7 h / Reflux 3.2: 75 °C View Scheme
参考文献
Chemical Communications, , vol. 47, # 35 p. 9903 - 9905
反应条件
1: 90 percent / H2 / Pd / diethyl ether / 24 h 2: 91 percent / CH3ONa / methanol / 0.5 h / Ambient temperature 3: 73 percent / TPP, DEAD, HN3 / benzene / 0.5 h / 60 °C 4: 1) LiAlH4 / 1) ether, 10 min, r.t., 2) pyridine, 3 h, r.t. 5: cationic exchanger (H(+)) / methanol / 24 h View Scheme
参考文献
Schmid, Walther; Zbiral, Erich
Monatshefte fuer Chemie, 1983 , vol. 114, p. 1253 - 1258
反应条件
1: 98 percent / H2 / Pd-C / ethyl acetate / 20 h / 20 °C / 1810.02 Torr 2: 99 percent / H2O; triethylamine / methanol / 3 h / 20 °C View Scheme
参考文献
Watterson, Mark P.; Pickering, Lea; Smith, Martin D.; Hudson, Sarah J.; Marsh, Paul R.; Mordaunt, Jacqueline E.; Watkin, David J.; Newman, Christopher J.; Fleet, George W. J.
Tetrahedron Asymmetry, 1999 , vol. 10, # 10 p. 1855 - 1859
