反应条件
1.1: 94 percent / PBr3 / toluene / 0 - 20 °C
2.1: 100 percent / NaN3 / dimethylsulfoxide / 3.5 h / 50 °C
3.1: H2 / Pd/C / methanol / 0.5 h
4.1: polystyrene-N(CH2CH2OH)2 / tetrahydrofuran / 3 h / 20 °C
4.2: HOBT; diisopropylcarbodiimide / 1-methyl-pyrrolidin-2-one / 16 h / 20 °C
4.3: H2O / tetrahydrofuran / 0.17 h / 20 °C
View Scheme
参考文献
Lan, Ping; Berta, Daniela; Porco Jr., John A.; South, Michael S.; Parlow, John J.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9678 - 9686
