6-[(氨基羰基)氨基]己酸合成路线 （共 9 条）
参考文献
Thomas; Goerne
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1914 , vol. 92, p. 172
反应条件
sodium hydroxide in methanol
参考文献
Schreiber,J.; Witkop,B.
Journal of the American Chemical Society, 1964 , vol. 86, p. 2441 - 2445
参考文献
McMeekin; Cohn; Weare
Journal of the American Chemical Society, 1936 , vol. 58, p. 2147
反应条件
1: H2O
2: aqueous H2O2
3: aqueous HNO3; NaNO2
4: water; NH3
View Scheme
参考文献
McKay et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 1510,1512,1515
反应条件
1: aq. NaOH / 2 h / 118 - 120 °C
2: 10 h / 107 - 108 °C
View Scheme
参考文献
Zil'berman, E. N.; Konilina, A. N.; Spasskaya, R. I.; Matveeva, G. N.
J. Appl. Chem. USSR (Engl. Transl.), 1983 , vol. 56, # 10 p. 2389 - 2392,2225 - 2228
参考文献
Thomas; Goerne
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1914 , vol. 92, p. 172
反应条件
T=107 - 108°C; 10 h;
参考文献
Zil'berman, E. N.; Konilina, A. N.; Spasskaya, R. I.; Matveeva, G. N.
J. Appl. Chem. USSR (Engl. Transl.), 1983 , vol. 56, # 10 p. 2389 - 2392,2225 - 2228
反应条件
sodium hydroxide
multistep reaction, influence of temperature, conc. of NaOH and method of loading; Product distribution;
参考文献
Zil'berman, E. N.; Konilina, A. N.; Spasskaya, R. I.; Matveeva, G. N.
J. Appl. Chem. USSR (Engl. Transl.), 1983 , vol. 56, # 10 p. 2389 - 2392,2225 - 2228
反应条件
hydrogenchloride in tetrahydrofuran
T=20°C; Biginelli reaction; 96 h;
参考文献
Werner, Stefan; Turner, David M.; Lyon, Michael A.; Huryn, Donna M.; Wipf, Peter
Synlett, 2006 , # 14 p. 2334 - 2338
