(+/-)-1-(1,3-苯并二氧戊环-5-基)-2-溴-1-戊酮合成路线 （共 3 条）
反应条件
bromine; acetic acid T=20°C; 2 h;
参考文献
Randox Laboratories Ltd.; Lowry, Philip; Benchikh, Elouard; McConnell, Ivan; Fitzgerald, Peter
Patent: EP2626358 A1, 2013 ;
Location in patent: Paragraph 0025 ;
反应条件
1: 1) NaH / 1) DMSO, r.t., 15 min, 2) THF, r.t., 2 h 2: 98 percent / N-bromosuccinimide, H2O / dimethylsulfoxide / 0.25 h / Ambient temperature 3: 82 percent / Jones reagent / acetone / 0.25 h / 0 °C View Scheme
参考文献
Yamauchi, Satoshi; Taniguchi, Eiji
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 11 p. 1751 - 1759
反应条件
1: 98 percent / N-bromosuccinimide, H2O / dimethylsulfoxide / 0.25 h / Ambient temperature 2: 82 percent / Jones reagent / acetone / 0.25 h / 0 °C View Scheme
参考文献
Yamauchi, Satoshi; Taniguchi, Eiji
Bioscience, Biotechnology, and Biochemistry, 1992 , vol. 56, # 11 p. 1751 - 1759
