2,6-二甲氧基苯甲酸合成路线 （共 118 条）
反应条件
1-n-butyl-3-methylimidazolium hexafluorophosphate T=80°C; 2.5 h;
参考文献
Yoshino, Tomonori; Imori, Satomi; Togo, Hideo
Tetrahedron, 2006 , vol. 62, # 6 p. 1309 - 1317
反应条件
1: 4-(N,N-dimethylamino)pyridinium chlorosulphite chloride / CH2Cl2 / 0.5 h / -20 °C 2: pyridine / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Arrieta, A.; Garcia, T.; Palomo, C.
Synthetic Communications, 1982 , vol. 12, # 14 p. 1139 - 1146
反应条件
1: potassium tert-butylate / ethanol / 3 h / |Inert atmosphere 2: tris (α-naphthyl)phosphine; 1,10-phenanthroline; copper(l) iodide; palladium (II) bromide / 1-methyl-pyrrolidin-2-one; 1,3,5-trimethyl-benzene / 16 h / 150 °C / |Inert atmosphere View Scheme
参考文献
Tang, Jie; Goossen, Lukas J.
Organic Letters, 2014 , vol. 16, # 10 p. 2664 - 2667
反应条件
hydrogen bromide; acetic acid in chloroform 20 h; Ambient temperature;
参考文献
Kung; Kasliwal; Pan; Mach; Guo
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 1039 - 1043
反应条件
aluminium trichloride
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 124, p. 322
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 124, p. 322
反应条件
1: 60 percent / HBr, AcOH / CHCl3 / 20 h / Ambient temperature 2: 70 percent / ICl / acetic acid / 1.) reflux, 3 h, 2.) room temperature, 18 h 3: SOCl2, DMF / CHCl3 / 2 h / Heating 4: CHCl3 / 2 h View Scheme
参考文献
Kung; Kasliwal; Pan; Mach; Guo
Journal of Medicinal Chemistry, 1988 , vol. 31, # 5 p. 1039 - 1043
反应条件
aluminium trichloride; chlorobenzene
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 121, p. 262
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 124, p. 320
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 121, p. 262
Journal fuer Praktische Chemie (Leipzig), 1929 , vol. <2> 124, p. 320
反应条件
1: 85 percent / Br2 / CHCl3; dioxane / 2 h / Ambient temperature 2: SOCl2 / 0.5 h / Heating 3: 10N aq. NaOH / CHCl3 / 0.17 h / Heating View Scheme
参考文献
Florvall, Lennart; Oegren, Sven-Ove
Journal of Medicinal Chemistry, 1982 , vol. 25, # 11 p. 1280 - 1286
