Fmoc-L-丙氨酸-甲酯合成路线 (共 4 条)
反应条件
1: With Corey's ylide in tetrahydrofuran T=20°C; 0.333333 h; Inert atmosphere; 2: With water in tetrahydrofuran Inert atmosphere;
参考文献
Spinella, Mariagiovanna; De Marco, Rosaria; Belsito, Emilia L.; Leggio, Antonella; Liguori, Angelo
Tetrahedron, 2013 , vol. 69, # 8 p. 2010 - 2016
反应条件
trimethyltin hydroxide in 1,2-dichloro-ethane T=80°C; 5 h;
参考文献
Nicolaou; Estrada, Anthony A.; Zak, Mark; Lee, Sang Hyup; Safina, Brian S.
Angewandte Chemie - International Edition, 2005 , vol. 44, # 9 p. 1378 - 1382
反应条件
hydrogenchloride; aluminium trichloride; sodium hydrogencarbonate in chloroform; water; toluene T=20°C; deprotection; 3 h;
参考文献
Leggio, Antonella; Liguori, Angelo; Napoli, Anna; Siciliano, Carlo; Sindona, Giovanni
European Journal of Organic Chemistry, 2000 , # 4 p. 573 - 575
反应条件
sodium tetrahydroborate in methanol; diethyl ether T=20°C; 1 h;
参考文献
Somlai, Csaba; Peter, Antal; Forgo, Peter; Penke, Botond
Synthetic Communications, 2003 , vol. 33, # 11 p. 1815 - 1820