2-乙基-3,4,5,6-四氢吡啶合成路线 （共 4 条）
反应条件
lithium diisopropyl amide in tetrahydrofuran 1.) 0 deg C, 2.) -78 deg C, 1 h;
参考文献
Houk, K.N.; Strozier, Robert W.; Rondan, Nelson G.; Fraser, Robert R.; Chuaqui-Offermanns, N.
Journal of the American Chemical Society, 1980 , vol. 102, # 4 p. 1426 - 1429
反应条件
1: EtBr; TMEDA / tetrahydrofuran / 12 h / -78 °C 2: 14.7 g / TFA / CH2Cl2 / 24 h / 20 °C View Scheme
参考文献
Fuganti, Claudio; Gatti, Francesco G.; Serra, Stefano
Tetrahedron, 2007 , vol. 63, # 22 p. 4762 - 4767
反应条件
1: NCS / CCl4 / Heating 2: NaOMe / methanol / 15 h / Ambient temperature View Scheme
参考文献
De Kimpe, Norbert; Keppens, Marian; Fonck, Gwendolien
Chemical Communications, 1996 , # 5 p. 635 - 636
反应条件
1: With tert.-butylhydroperoxide; selenium(IV) oxide in dichloromethane
T=20°C; 9 h;
2: With triphenylphosphine in dichloromethane
T=0°C; 12 h;
参考文献
Fuganti, Claudio; Gatti, Francesco G.; Serra, Stefano
Tetrahedron, 2007 , vol. 63, # 22 p. 4762 - 4767
