2-(3,4-二甲氧基苯基)-5,7-二羟基-3-甲氧基-4-色酮合成路线 （共 4 条）
反应条件
1: With triethylamine Allan-Robinson condensation; 0.0833333 h; Heating; 2: With potassium hydroxide in methanol 0.333333 h; sonication;
参考文献
SHENOGEN PHARMA GROUP LTD.
Patent: WO2009/129372 A1, 2009 ;
Location in patent: Page/Page column 37 ;
反应条件
1.1: 89 percent / methanesulfonyl chloride; Et3N / tetrahydrofuran / 0 °C 2.1: Et3N / 0.08 h / Heating 2.2: 74 percent / KOH / methanol / 0.33 h / sonication View Scheme
参考文献
Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804
反应条件
pyridine; potassium carbonate
参考文献
Lynch et al.
Journal of the Chemical Society, 1952 , p. 2063,2067
反应条件
potassium carbonate in acetone
5 h; Heating;
参考文献
Daskiewicz, Jean-Baptiste; Depeint, Flore; Viornery, Lionel; Bayet, Christine; Comte-Sarrazin, Geraldine; Comte, Gilles; Gee, Jennifer M.; Johnson, Ian T.; Ndjoko, Karine; Hostettmann, Kurt; Barron, Denis
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2790 - 2804
