4-(4-氯苯甲酰氯)吡啶合成路线 （共 7 条）
反应条件
aluminium trichloride; thionyl chloride in chlorobenzene
反应条件
hydrogenchloride 1.) ether, toluene, 80 deg C, 1.5 h, 2.) ether, toluene; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 12 p. 1499 - 1507
反应条件
aluminium trichloride
参考文献
Farmaco, Edizione Scientifica, , vol. 12, p. 853,862
反应条件
diethyl ether; benzene
参考文献
Cavallini et al.
Farmaco, Edizione Scientifica, 1957 , vol. 12, p. 853,862
反应条件
1: 80 percent / NaBH4 / ethanol / 0.5 h / Heating
2: 76 percent / H2; aq. HCl / PtO2 / ethanol / 0.5 h / 2280 Torr
View Scheme
参考文献
Lyles-Eggleston; Altundas; Xia; Sikazwe; Fan; Yang; Li; Zhang; Zhu; Schmidt; Vanase-Frawley; Shrihkande; Villalobos; Borne; Ablordeppey
Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 497 - 508
反应条件
magnesium
1) ether, 2) ether, rt; Multistep reaction;
参考文献
Nagarajan, K.; Talwalker, P. K.; Shah, R. K.; Shenoy, S. J.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 112 - 118
反应条件
(i) Mg, (ii) /BRN= 143470/; Multistep reaction;
参考文献
Sauter,F. et al.
Monatshefte fuer Chemie, 1976 , vol. 107, p. 495 - 499
