methanol; nickel T=40 - 50°C; P=44130.5 Torr; Hydrogenation;

in water T=15°C; Irradiation;

triethylamine; p-toluenesulfonyl chloride in chloroform-d1; water 12 h; Ambient temperature;

in cyclohexane T=15°C; Irradiation;

1: H2O 2: aq.-ethanolic NaOH View Scheme

1: H2O 2: aq.-ethanolic NaOH; aqueous H2O2 3: KBrO; aqueous KOH View Scheme

Multi-step reaction with 3 steps 1: methanol / 12 h / 95 °C / |Inert atmosphere2: palladium 10 on activated carbon; lithium carbonate; hydrogen / ethanol / 12 h / 23 °C / |Inert atmosphere3: m-chloro-peroxy-benzoic acid / dichloromethane / 12 h / |Inert atmosphere