3,5-二甲基-4-硝基吡唑合成路线 （共 29 条）
反应条件
sodium hydroxide; dimethyl sulfate
参考文献
Huettel et al.
Chemische Berichte, 1955 , vol. 88, p. 1577,1583
参考文献
Musante; Stener
Gazzetta Chimica Italiana, 1959 , vol. 89, p. 1579,1594
反应条件
methanol; potassium hydroxide
参考文献
Musante; Stener
Gazzetta Chimica Italiana, 1959 , vol. 89, p. 1579,1594
参考文献
Russian Chemical Bulletin, , vol. 56, # 11 p. 2175 - 2183
反应条件
1: amalgamated aluminium; diethyl ether 2: sodium nitrite; hydrochloric acid / Diazotization.Verkochen mit Kaliumjodid View Scheme
参考文献
Journal of the Chemical Society, , vol. 123, p. 1315
反应条件
nitric acid; acetic acid
anschl. mit Acetanhydrid;
参考文献
Huettel; Buechele
Chemische Berichte, 1955 , vol. 88, p. 1586,1590
反应条件
1: hydrochloric acid; tin / 100 °C
2: ethyl nitrite; aqueous-alcoholic hydrochloric acid
View Scheme
参考文献
Morgan; Reilly
Journal of the Chemical Society, 1914 , vol. 105, p. 441
反应条件
1: caesium carbonate / acetonitrile / 3 h / 90 °C / Reflux
2: hydrogen / platinum(IV) oxide / ethyl acetate; ethanol / 30 h / 20 °C
View Scheme
参考文献
ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; BOSS, Christoph; BROTSCHI, Christine; GUDE, Markus; HEIDMANN, Bibia; SIFFERLEN, Thierry; WILLIAMS, Jodi, T.
Patent: WO2012/110986 A1, 2012 ;
WO 2012/110986 A1
反应条件
potassium permanganate
参考文献
Huettel et al.
Chemische Berichte, 1955 , vol. 88, p. 1577,1583
