1-苯基-1H-1,2,3-噻唑合成路线 （共 31 条）
反应条件
1: 2-chloro-ethanol With tetra-(n-butyl)ammonium iodide; potassium iodide in tetrahydrofuran; N,N-dimethyl-formamide
T=80°C; 24 h; polystyrene/1percent divinylbenzene resin; Inert atmosphere;
2: With acetic anhydride; 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran
T=0 - 20°C; polystyrene/1percent divinylbenzene resin;
3: diazoaminobenzene Further stages;
参考文献
Huang, Zhenzhong; Wang, Ruiling; Sheng, Shouri; Zhou, Ruyi; Cai, Mingzhong
Reactive and Functional Polymers, 2013 , vol. 73, # 1 p. 224 - 227
反应条件
1: in dimethyl sulfoxide
T=20°C; 0.25 h;
2: With water in dimethyl sulfoxide
参考文献
Jiang, Yubo; Kuang, Chunxiang; Yang, Qing
Tetrahedron, 2011 , vol. 67, # 2 p. 289 - 292
反应条件
caesium carbonate; copper(II) oxide; iron (III) acetylacetonate in N,N-dimethyl-formamide
T=90°C; 30 h;
参考文献
Taillefer, Marc; Xia, Ning; Ouali, Armelle
Angewandte Chemie - International Edition, 2007 , vol. 46, # 6 p. 934 - 936
反应条件
copper(l) iodide; triethylamine in dimethyl sulfoxide
T=20°C; P=760.051 Torr; 24 h;
参考文献
Wu, Lu-Yong; Xie, Yong-Xin; Chen, Zi-Sheng; Niu, Yan-Ning; Liang, Yong-Min
Synlett, 2009 , # 9 p. 1453 - 1456
反应条件
caesium carbonate; Fe(acac)3; copper(II) oxide in N,N-dimethyl-formamide
T=90°C; 30 h; sealed tube; Conversion of starting material;
参考文献
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.); Ecole Nationale Superieure de Chimie de Montpellier
Patent: WO2008/4088 A2, 2008 ;
Location in patent: Page/Page column 49-50 ;
反应条件
potassium carbonate; copper(II) sulfate; sodium L-ascorbate in methanol; water
T=20°C; Huisgen 1,3-dipolar cycloaddition; 24 h;
参考文献
Kumar, A. Sudheer; Ghule, Vikas D.; Subrahmanyam; Sahoo, Akhila K.
Chemistry - A European Journal, 2013 , vol. 19, # 2 p. 509 - 518
反应条件
copper(l) iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium L-ascorbate in N,N-dimethyl-formamide
T=25°C; 14 h; Sealed tubeInert atmosphere;
参考文献
Xu, Mei; Kuang, Chunxiang; Wang, Zhuo; Yang, Qing; Jiang, Yubo
Synthesis, 2011 , # 2 art. no. F18110SS, p. 223 - 228
反应条件
triethylamine in methanol
T=0°C; 3 h;
参考文献
Harada, Katsumasa; Oda, Mizuho; Matsushita, Aklo; Shirai, Masashi
Heterocycles, 1998 , vol. 48, # 4 p. 695 - 702
反应条件
triethylamine in methanol
T=0°C; 1 h;
参考文献
Harada, Katsumasa; Oda, Mizuho; Matsushita, Aklo; Shirai, Masashi
Heterocycles, 1998 , vol. 48, # 4 p. 695 - 702
反应条件
copper(l) iodide; Na-ascorbate in water; acetonitrile
T=20°C; 16 h;
参考文献
Jiang, Yubo; Kuang, Chunxiang; Yang, Qing
Synlett, 2009 , # 19 p. 3163 - 3166
